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PAN-AMIN SG
Composition
Each 1000 mL contains:
| D-Sorbitol: | 50.0 g |
| L-Arginine: | 6.6 g |
| L-Histidine: | 3.0 g |
| L-Isoleucine: | 5.5 g |
| L-Leucine: | 12.3 g |
| L-Lysine: | 14.9 g |
| L_Methionine: | 7.1 g |
| L-Phenylalanine: | 8.7 g |
| L-Threonine: | 5.4 g |
| L-Tryptophan: | 1.8 g |
| L-Valine: | 6.1 g |
| Glycine (Aminoacetic acid): | 10.0 g |
| Water for Injection: | q.s. |
| Free AA: | 8.14% (w/v) |
| Essential AA (E): | 6.18% (w/v) |
| Non-Essential AA (N): | 1.96% (w/v) |
| E/N: | 3.15 |
| Total Nitrogen: | 13 g/L |
| Na+ | 12 mEq/L |
| Cl- | 153 mEq/L |
| Osmolarity: | 1232 mOsm/L |
Indications
Recommended for provision of amino acids and energy in patients who require intravenous nutrition. Such conditions include surgery, infections, trauma, burns, prolonged disorders of the gastrointestinal tract, hypoproteinemia, malnutrition, preparation of patients for surgery, chemotherapy or radiation therapy, prolonged coma or refusal to eat.
Dosage and Administration
Generally proteins are provided in a daily dose of 0.8-1.0 g/kg for maintenance and 1.2-2.0 g/kg in catabolic states. The usual adult dosage of Pan-Amin SG is 500 ml via intravenous infusion over 200-250 minutes (40-30 drops/min). The dosage should be increased or decreased according to the age and body weight of the patient and the severity of the condition. The infusion rate should be slowed in elderly and severely ill patients. The maximal daily dose of sorbitol should not exceed 100 g. Slow intravenous administration is recommended.
Contraindications
Hypersensitivity to any ingredient of the preparation. Hereditary fructose intolerance, hepatic coma, azotemia, congestive cardiac failure, severe acidosis and disturbances of amino acid metabolism.
Precautions
Pan-Amin SG should be administered with care in patients with severe hepatic and renal disorders, diabetes mellitus and in elderly. It should be used in pregnant patients after careful assessment and only if the therapeutic benefits outweigh any potential risks associated with the treatment.
Adverse Events
Hypersensitivity, chest discomfort and palpitations may occur. Occasionally nausea, vomiting, chills, fever, phlebitis and electrolyte imbalance may occur.
Packaging
500 mL glass bottles, packed in unit boxes.
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